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Can the AMD Instinct MI350X run GLM-5.3-Flash?

GLM-5.3-Flash · AMD Instinct MI350X · 8,192 ctx · whole model residentQ6_K sizesize rangeSpeedestimate

IT FITS

Yes. 7 of 9 formats evaluated fit in 288 GB, at 8,192 tokens. No published file exists for this pair, so every size is rebuilt from the pinned architecture. The best quality that fits is Q6_K, needing 265.0 GB and running at an estimated 493 tokens per second.

Fitting in memory is not the same as loading. Whether the runtime and version you have supports this architecture and format on this machine has not been tested here.

7/9formats that fit
288 GBdevice memory
265.0 GBneeded at best quality
~493tokens per second, estimatedFaster than you read
8000GB/s bandwidth

How long a conversation. At Q6_K, this pair holds 1,048,576 tokens of context — roughly 786,432 words — needing 279.6 GB. That is zai-org's own configured maximum of 1,048,576 tokens, not the card running out. A larger device does not extend it; a documented RoPE or YaRN extension might, and is a separate question from this one.

Every format evaluated

No published file exists for this pair, so every size is rebuilt from the pinned architecture. The Basis column says which is which for each row. Decode and first-token figures are calibrated estimates, not runs on this card.

FormatNeedsOf 288 GBFitsDecodeFirst tokenBasis
FP16644.0 GB224%short by 356.0 GBdoes not run—size range
Q8_0342.8 GB119%short by 54.8 GBdoes not run—size range
Q6_K265.0 GB92%yes~493 tok/s~1.1 ssize range
Q5_K_M230.6 GB80%yes~567 tok/s~1.1 ssize range
Q5_0225.3 GB78%yes~579 tok/s~1.1 ssize range
Q4_K_M198.3 GB69%yes~660 tok/s~1.1 ssize range
Q4_0188.0 GB65%yes~694 tok/s~1.1 ssize range
Q3_K_M161.8 GB56%yes~797 tok/s~1.1 ssize range
Q2_K128.3 GB45%yes~1033 tok/s~1.1 ssize range

Sized at 8,192 tokens of context with the whole model resident — weights, the KV cache and the runtime reserve, offload off. Speed is only quoted for a format that fits: a rate for a configuration that cannot load is not a fact about anything.

Why the first-token figure is the same on every row

First token is modelled from the arithmetic the prompt requires, and that count does not change with the weight format — which is why it reads the same on every row. Real prefill does vary by format, because a quantized matmul is a different kernel; this model does not capture that, and the figure should be read as an order of magnitude rather than a ranking between formats.

What the labels mean
published data
Read from a published source — a file's byte count, a model's configuration or a manufacturer's specification — or exact arithmetic on such values. Not a measurement on a machine.
reconstructed size
Weight size reconstructed from the pinned architecture, because no published file exists.
size range
Only a lower and an upper bound are claimed for this weight size.
estimate
Calculated from sourced inputs by a stated method; an estimate, not a measurement.
Change anything

This page fixes the context at 8,192 tokens and one device. Batch, concurrent users, KV-cache format, clusters and rental cost are all in the calculator, already set to this pairing.

Open in the calculator →Everything the AMD Instinct MI350X runs

Where these numbers come from

GLM-5.3-Flash’s architecture is read from its publisher’s own config.json at a pinned revision, and the AMD Instinct MI350X’s 288 GB and 8000 GB/s come from the manufacturer’s specification. How far each figure can be trusted is published, per format and worst case included, on the accuracy scorecard.

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  -H "Authorization: Bearer $LLMB_KEY" -H "content-type: application/json" \
  -d '{"model":"zai-org-glm-5-3-flash","quantization":"Q6_K","context":8192,"hardware":"amd-instinct-mi350x"}'

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  data-model="zai-org-glm-5-3-flash" data-quantization="Q6_K"
  data-hardware="amd-instinct-mi350x" data-context="8192"></script>

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catalogue 2026-10-03models 327devices 135