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Can the AMD Instinct MI300X Accelerator run gemma-4-E2B-it?

gemma-4-E2B-it · AMD Instinct MI300X Accelerator · 8,192 ctx · whole model residentFP16 sizesize rangeSpeedestimate

IT FITS

Yes. 9 of 9 formats evaluated fit in 192 GB, at 8,192 tokens. No published file exists for this pair, so every size is rebuilt from the pinned architecture. The best quality that fits is FP16, needing 11.1 GB and running at an estimated 1229 tokens per second.

Fitting in memory is not the same as loading. Whether the runtime and version you have supports this architecture and format on this machine has not been tested here.

9/9formats that fit
192 GBdevice memory
11.1 GBneeded at best quality
~1229tokens per second, estimatedFaster than you read
5300GB/s bandwidth

How long a conversation. At FP16, this pair holds 131,072 tokens of context — roughly 98,304 words — needing 12.0 GB. That is Google's own configured maximum of 131,072 tokens, not the card running out. A larger device does not extend it; a documented RoPE or YaRN extension might, and is a separate question from this one.

Every format evaluated

No published file exists for this pair, so every size is rebuilt from the pinned architecture. The Basis column says which is which for each row. Decode and first-token figures are calibrated estimates, not runs on this card.

FormatNeedsOf 192 GBFitsDecodeFirst tokenBasis
FP1611.1 GB6%yes~1229 tok/s~0.22 ssize range
Q8_06.32 GB3%yes~2269 tok/s~0.22 ssize range
Q6_K5.08 GB3%yes~2905 tok/s~0.22 ssize range
Q5_K_M4.53 GB2%yes~3228 tok/s~0.22 ssize range
Q5_04.45 GB2%yes~3285 tok/s~0.22 ssize range
Q4_K_M4.02 GB2%yes~3606 tok/s~0.22 ssize range
Q4_03.85 GB2%yes~3747 tok/s~0.22 ssize range
Q3_K_M3.44 GB2%yes~4113 tok/s~0.22 ssize range
Q2_K2.90 GB2%yes~4879 tok/s~0.22 ssize range

Sized at 8,192 tokens of context with the whole model resident — weights, the KV cache and the runtime reserve, offload off. Speed is only quoted for a format that fits: a rate for a configuration that cannot load is not a fact about anything.

Why the first-token figure is the same on every row

First token is modelled from the arithmetic the prompt requires, and that count does not change with the weight format — which is why it reads the same on every row. Real prefill does vary by format, because a quantized matmul is a different kernel; this model does not capture that, and the figure should be read as an order of magnitude rather than a ranking between formats.

What the labels mean
published data
Read from a published source — a file's byte count, a model's configuration or a manufacturer's specification — or exact arithmetic on such values. Not a measurement on a machine.
reconstructed size
Weight size reconstructed from the pinned architecture, because no published file exists.
size range
Only a lower and an upper bound are claimed for this weight size.
estimate
Calculated from sourced inputs by a stated method; an estimate, not a measurement.
Change anything

This page fixes the context at 8,192 tokens and one device. Batch, concurrent users, KV-cache format, clusters and rental cost are all in the calculator, already set to this pairing.

Open in the calculator →Everything the AMD Instinct MI300X Accelerator runsBest models for 192 GB

Where these numbers come from

gemma-4-E2B-it’s architecture is read from its publisher’s own config.json at a pinned revision, and the AMD Instinct MI300X Accelerator’s 192 GB and 5300 GB/s come from the manufacturer’s specification. How far each figure can be trusted is published, per format and worst case included, on the accuracy scorecard.

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catalogue 2026-10-03models 327devices 135